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Publications


 Recent Publications 

  • Neale MC, Clark, S.L., Dolan, C.V., Hunter, M. Regime switching models of substance use: Time-varying and second-order Markov models and individual probability plots. Structural Equation Modeling. 2016 Mar 1; 23(2): 221-233.  PubMed PMID: 26924921; PubMed Central PMCID: PMC4767507.
  • McClay JL, Shabalin, A.A., Dozmorov, M.G., Adkins, D.E., Kumar, G., Nerella, S., Clark,, S.L. B, S.E., Hultman, C.M., Magnusson, P.K., Sullivan, P.F., Aberg, K.A., van den Oord, E.J. High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction. Genome Biology 2015 Dec 23;16:291. doi: 10.1186/s13059-015-0842-7. PubMed-in process PMID: 26699738 PubMed Central PMCID: PMC4699364.
  • Shabalin AA, Aberg KA, van den Oord EJ. Candidate gene methylation studies are at high risk of erroneous conclusions. Epigenomics. 2015; 7 (1): 13-5. doi: 10.2217/epi.14.70. PubMed PMID: 25687462.
  • Kumar G, Clark SL, McClay JL, Shabalin AA, Adkins DE, Xie L, Chan R, Nerella S, Kim Y, Sullivan PF, Hultman CM, Magnusson PK, Aberg KA, van den Oord EJ. Refinement of schizophrenia GWAS loci using methylome-wide association data. Human genetics. 2015 Jan; 134 (1): 77-87. PubMed PMID: 25284466; PubMed Central PMCID: PMC4282961.
  • Byrne EM, Psychiatric Genetics Consortium Major Depressive Disorder Working G, Raheja UK, Stephens SH, Heath AC, Madden PA, Vaswani D, Nijjar GV, Ryan KA, Youssufi H, Gehrman PR, Shuldiner AR, Martin NG, Montgomery GW, Wray NR, Nelson EC, Mitchell BD, Postolache TT (van den Oord EJCG 124 of 133 authors). Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder. The Journal of clinical psychiatry. 2015 Feb; 76 (2): 128- 34. PubMed PMID: 25562672; PubMed Central PMCID: PMC4527536.
  • Maier R, Moser G, Chen GB, Ripke S, Cross-Disorder Working Group of the Psychiatric Genomics C, Coryell W, Potash JB, Scheftner WA, Shi J, Weissman MM, Hultman CM, Landen M, Levinson DF, Kendler KS, Smoller JW, Wray NR, Lee SH (van den Oord EJCG 352 of 380 authors). Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. American journal of human genetics. 2015 Feb; 96 (2): 283-94. PubMed PMID: 25640677; PubMed Central PMCID: PMC4320268.
  • Network, Pathway Analysis Subgroup of Psychiatric Genomics C. (van den Oord EJCG) Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature neuroscience. 2015 Feb; 18 (2): 199-209. PubMed PMID: 25599223; PubMed Central PMCID: PMC4378867.
  • Consortium GT. Human genomics (Shabalin AA 22 of 139 authors). The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science May. 2015. PubMed PMID: 25954001; PubMed Central PMCID: PMC4547484.
  • Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trumbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED, Major Depressive Disorder Working Group of the Psychiatric Genomics C, Ruepp A, Muller-Myhsok B, Hariri AR, Binder EB, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC (van den Oord EJCG 130 of 139 authors). Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. Neuron. 2015 June; 86 (5): 1189-202. PubMed PMID: 26050039; PubMed Central PMCID: PMC4490780.
  • Aberg KA, Xie L, Chan RF, Zhao M, Pandey AK, Kumar G, Clark SL, van den Oord EJ. Evaluation of Methyl-Binding Domain Based Enrichment Approaches Revisited. PloS one. 2015 July; 10 (7):e0132205. PubMed PMID: 26177298; PubMed Central PMCID: PMC4503759.
  • Genetics of Personality C, de Moor MH, van den Berg SM, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Gordon SD, Hansell NK, Hart AB, Seppala I, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abecasis GR, Adkins DE, Agrawal A, Allik J, Appel K, (Adkins DE 27 of 119 authors). Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. JAMA psychiatry. 2015 July; 72 (7): 642-50. PubMed PMID: 25993607; PubMed Central PMCID: PMC4667957.
  • Adkins DE, Clark SL, Copeland WE, Kennedy M, Conway K, Angold A, Maes H, Liu Y, Kumar G, Erkanli A, Patkar AA, Silberg J, Brown TH, Fergusson DM, Horwood LJ, Eaves L, van den Oord EJ, Sullivan PF, Costello EJ. Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood. Twin research and human genetics : the official journal of the International Society for Twin Studies. 2015 Aug; 18 (4):335-47. PubMed PMID: 26081443.
  • Clark SL, McClay JL, Adkins DE, Aberg KA, Kumar G, Nerella S, Xie L, Collins AL, Crowley JJ, Quakenbush CR, Hillard CE, Gao G, Shabalin AA, Peterson RE, Copeland WE, Silberg JL, Maes H, Sullivan PF, Costello EJ, van den Oord EJ. Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses. Nicotine & tobacco research: official journal of the Society for Research on Nicotine and Tobacco. 2015 Aug. PubMed PMID: 26283763.
  • Clark SL, Aberg KA, Nerella S, Kumar G, McClay JL, Chen W, Xie LY, Harada A, Shabalin AA, Gao G, Bergen SE, Hultman CM, Magnusson PK, Sullivan PF, van den Oord EJ. Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use. Alcoholism, clinical and experimental research. 2015 Aug; 39 (8):1396-405. PubMed PMID: 26146898; PubMed Central PMCID: PMC4515164.
  • McClay JL, Vunck SA, Batman AM, Crowley JJ, Vann RE, Beardsley PM, van den Oord EJ. Neurochemical Metabolomics Reveals Disruption to Sphingolipid Metabolism Following Chronic Haloperidol Administration. Journal of neuroimmune pharmacology: the official journal of the Society on NeuroImmune Pharmacology. 2015 Sept; 10 (3): 425-34. PubMed PMID: 25850894; PubMed Central PMCID: PMC4546545.
  • van den Berg SM, de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Gordon SD, Hansell NK, Hart AB, Seppala I, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abdellaoui A, Abecasis GR, Adkins DE, Agrawal A, Allik J, Appel K, (Adkins DE 27 of 122 authors). Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Behavior genetics. 2015 Sept. PubMed PMID: 26362575.
  • Cho SB, Llaneza DC, Adkins AE, Cooke M, Kendler KS, Clark SL, Dick DM. Patterns of Substance Use Across the First Year of College and Associated Risk Factors. Frontiers in psychiatry. 2015 Oct; 6:152. PubMed PMID: 26578984; PubMed Central PMCID: PMC4621385.
  • Clark SL, Gillespie NA, Adkins DE, Kendler KS, Neale MC. Psychometric modeling of abuse and dependence symptoms across six illicit substances indicates novel dimensions of misuse. Addictive behaviors. 2015 Oct; 53:132-40. Epub. PubMed PMID: 26517709.
  • Sudmant PH, Rausch T, Gardner EJ, Handsaker RE, Abyzov A, Huddleston J, Zhang Y, Ye K, Jun G, Hsi-Yang Fritz M, Konkel MK, Malhotra A, Stutz AM, Shi X, Paolo Casale F, Chen J, Hormozdiari F, Dayama G, Chen K, Malig M, Chaisson MJ, Walter K, Meiers S, Kashin S, Garrison E, Auton A, Lam HY, Jasmine Mu X, Alkan C, Antaki D, (Shabalin AA 62 of 83 authors). An integrated map of structural variation in 2,504 human genomes. Nature. 2015 Oct; 526 (7571):75-81. PubMed PMID: 26432246; PubMed Central PMCID: PMC4617611.
  • Luo XJ, Mattheisen M, Li M, Huang L, Rietschel M, Borglum AD, Als TD, van den Oord EJ, Aberg KA, Mors O, Mortensen PB, Luo Z, Degenhardt F, Cichon S, Schulze TG, Nothen MM, i P-GSCZwg, Moo DSSCZC, Su B, Zhao Z, Gan L, Yao YG. Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function. Schizophrenia bulletin. 2015 Nov; 41 (6): 1294-308. PubMed PMID: 25759474; PubMed Central PMCID: PMC4601704.
  • van den Oord EJ, Clark SL, Xie LY, Shabalin AS, Dozmorov MG, Kumar G, Swedish Schizophrenia C, Vladimirov VI, Magnusson PK, Aberg KA. A Whole Methylome CpG-SNP Association Study of Psychosis in Blood and Brain Tissue. Schizophrenia bulletin. 2015 Dec. Epub. PubMed PMID: 26656881.

Updated March 2016