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2013 Publications


  • Adkins DE, McClay JL, Vunck SA, Batman AM, Vann RE, Clark SL, Souza RP, Crowley JJ, Sullivan PF, van den Oord EJ, Beardsley PM. (2013) Behavioral metabolomics analysis identifies novel neurochemical signatures in methamphetamine sensitizationGenes, Brain and Behavior Nov;12(8): 780-791. PMID: 24034544.
  • McClay JL, Aberg KA, Clark SL, Nerella S, Kumar G, Xie LY, Hudson AD, Harada A, Hultman CM, Magnusson PKE, Sullivan PF, van den Oord EJ. (2013) A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG enriched genomic fraction from blood in over 700 subjects, Human Molecular Genetics Oct 30. PMID: 24135035.
  • Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ, Banaschewski T, Barchas JD, Barnes MR, Barrett TB, Bass N, Battaglia A, et al. (van den Oord EJCG 366 of 371 authors) (2013) Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs, Nat Genet  Sep;45(9):984-94PMID: 23933821, PMCID: PMC3800159.
  • Aberg KA, Xie LY, McClay JL, Nerella S, Vunck S, Snider S, Bukszar J, Beardsley PM, van den Oord EJCG. (2013)Two models describing how methylome-wide studies in blood are informative for psychiatric conditions, Epigenomics  Aug;5(4):367-77) PMID: 23895651
  • Zhao Z, Webb BT, Jia P, Bigdeli TB, Maher BS, van den Oord E, Bergen SE, Amdur RL, O'Neill FA, Walsh D, Thiselton DL, Chen X, Pato CN; International Schizophrenia Consortium, Riley BP, Kendler KS, Fanous AH. (2013) Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis, PLoS One Jul;8(7):e67776. PMID: 23922650.
  • Aberg K, Liu Y, Bukszar J, McClay JL, Khachane AN, Andreassen OA, Blackwood D, Corvin A, Djurovic S, Gurling H, Ophoff R, Pato CN, Pato MT, Riley B, Webb T, Kendler KS, O'Donovan M, Craddock N, Kirov G, Owen M, Rujescu D, St Clair D, Werge T, Hultman CM, Delisi LE, Sullivan PF, van den Oord EJ. (2013) A comprehensive family-based replication study of schizophrenia genesJAMA Psychiatry Jun;70(6):573-81. PMID: 23894747.
  • Lonsdale J, Thomas J, Salvatore M, Phillips R, Lo E, Shad S, Hasz R, Walters G, Garcia F, Young N, Foster B, Moser M, Karasik E, Gillard B,Ramsey K, Sullivan S, Bridge J, Magazine H, Syron J, Fleming J, Siminoff L, Traino H, Mosavel M, Barker L, Jewell S, Rohrer D, Maxim D, Filkins D, Harbach P, Cortadillo E, et al. (Shabalin, A 97 of 136) (2013) The Genotype-Tissue Expression (GTEx) project. Nat Genet, Jun;6, 580-585. PMID: 23715323.
  • Aberg, K. A., Xie, L., Nerella, S., Copeland, W. E., Costello, E. J., and van den Oord, E. J. C. G. (2013) Higth quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spotEpigenetics May;8(5):542-7. PMID: 23644822, PMCID: PMC37412244.
  • Cross-Disorder Group of the Psychiatric Genomics Consortium, Smoller JW, Craddock N, Kendler K, Lee PH, Neale BM, Nurnberger JI, Ripke S, Santangelo S, Sullivan PF. (2013) Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis, Lancet Apr;381(9875):1371-9. PMID: 23453885.
  • Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O'Donovan MC, Furberg H; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium, Schork NJ, Andreassen OA, Dale AM. (2013) All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs, PLoS Genet Apr;9(4):e1003449. PMID: 23637621.
  • Costello, E. J., Eaves, L., Sullivan, P., Kennedy, M., Conway, K., Adkins, D. E., Angold, A., Clark, S. L., Erkanli, A., McClay, J. L., Copeland, W., Maes, H. H., Liu, Y., Patkar, A. A., Silberg, J., and van den Oord, E. (2013) Genes, environments, and developmental research: methods for a multi-site study of early substance abuseTwin Res Hum Genet Apr;16(2), 505-515. PMID: 23461817, PMCID: PMC3609892.
  • Guille, C., Clark, S. L., Amstadter, A. B., and Sen, S. (2013) Trajectories of depressive symptoms during medical internship: Insights into classes of depressive symptoms under conditions of stressActa Psychiatrica Scandinavia
  • Hettema, J. M., An, S. S., van den Oord, E. J., Neale, M. C., Kendler, K. S., and Chen, X. (2013) Genetic association between RGS1 and internalizing disordersPsychiatr Genet Apr;23(2), 56-60. PMID: 23324853, PMCID: PMC3606916.
  • McClay, J. L., Adkins, D. E., Vunck, S. A., Batman, A. M., Vann, R. E., Clark, S. L., Beardsley, P. M., and van den Oord, E. J. (2013) Large-scale neurochemical metabolomics analysis identifies multiple compounds associated with methamphetamine exposureMetabolomics Apr;9(2), 392-402. PMID: 23554582, PMCID: PMC3611962.
  • Ramasamy A, Trabzuni D, Gibbs JR, Dillman A, Hernandez DG, Arepalli S, Walker R, Smith C, Ilori GP, Shabalin AA, Li Y, Singleton AB, Cookson MR;NABEC, Hardy J; UKBEC, Ryten M, Weale ME. (2013) Resolving the polymorphism-in-probe problem is critical for correct interpretation of expression QTL studies. Nucleic Acids Res. Apr;7, EPUB. PMID: 23435227, PMCID: PMC3627570.  
  • Chen, W., Gao, G., Nerella, S., Hultman, C. M., Magnusson, P. K., Sullivan, P. F., Aberg, K. A., and van den Oord, E. J. (2013) MethylPCA: a toolkit to control for confounders in methylome-wide association studiesBMC Bioinformatics Mar;14: 74PMID: 23452721, PMCID: PMC3599654.
  • Clark, S. L., Souza, R. P., Adkins, D. E., Aberg, K., Bukszar, J., McClay, J. L., Sullivan, P. F., and van den Oord, E. J. (2013) Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment, Pharmacogenet Genomics Feb;23(2), 69-77PMID: 23241943.  
  • Adkins, D. E., Souza, R. P., Aberg, K., Clark, S. L., McClay, J. L., Sullivan, P. F., and van den Oord, E. J. (2013) Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*DPLoS One Feb;8, e55239. PMID 23405125, PMCID: PMC3566192.
  • van den Oord, E. J., Bukszar, J., Rudolf, G., Nerella, S., McClay, J. L., Xie, L. Y., and Aberg, K. A. (2013) Estimation of CpG coverage in whole methylome next-generation sequencing studiesBMC Bioinformatics Feb;14: 50. PMID: 23398781, PMCID: PMC3599116.
  • Terwisscha van Scheltinga, A. F., Bakker, S. C., van Haren, N. E., Derks, E. M., Buizer-Voskamp, J. E., Boos, H. B., Cahn, W., Hulshoff Pol, H. E., Ripke, S., Ophoff, R. A., Kahn, R. S., and Psychiatric Genomics Consortium (2013) Genetic schizophrenia risk variants jointly modulate total brain and white matter volume, Biol Psychiatry, Mar; 73, 525-531. PMID: 23039932, PMCID: PMC3573254.
  • van Scheltinga AF, Bakker SC, van Haren NE, Derks EM, Buizer-Voskamp JE, Cahn W, Ripke S; Psychiatric Genome-Wide Association Study (GWAS) Consortium, Ophoff RA, Kahn RS. (2013) Schizophrenia genetic variants are not associated with intelligence. Psychol Med, Dec;  43, 2563-70. PMID: 23410598.
  • Hargreaves A, Anney R, O'Dushlaine C, Nicodemus KK; Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ); Wellcome Trust Case Control Consortium 2, Gill M, Corvin A, Morris D, Donohoe G. (2013) The one and the many: effects of the cell adhesion molecule pathway on neuropsychological function in psychosis. Psychol Med, Epub Nov 28. PMID: 24284030