Department of Medicinal Chemistry

Discovering and developing new therapeutic agents and targets

Medicinal chemistry, a multidisciplinary field integrating chemistry and the life sciences, applies chemical principles to study biologically active substances such as therapeutically useful drugs, natural products, toxins and drugs of abuse. Our department offers advanced training in drug design and discovery, emphasizing areas such as cardiovascular drugs, central nervous system agents, antimicrobial targets, natural product biosynthesis, anti-cancer agents and biomolecule structure elucidation. With state-of-the-art molecular modeling facilities, synthetic organic chemistry laboratories, X-ray crystallographic equipment and high-field nuclear magnetic resonance spectrometers, our research is supported by cutting-edge technologies and collaborations with the Center for Drug Discovery.

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Degree Offerings

Our M.S. and Ph.D. programs offer an in-depth study of synthesizing, analyzing and designing pharmaceutical compounds.

Two current students celebrate the graduation of their Medicinal Chemistry peer at the Hooding and Diploma Ceremony while another graduate and their professor and mentor take photos of them posing together with flowers

Research

Our department is a leader in drug discovery and development.

Postdoctoral fellow Ennian Li presents research to industry partners at the school's Research Day

Courses

Review a list of medicinal chemistry courses on the VCU Bulletin site.

Students in the audience of a lecture hall share a laugh prior to the beginnning of a session at the Medicinal Chemistry Symposium

Graduate Student Association

Explore the alpha chapter of the nationally-recognized ACS MEDI Division.

Students and faculty in casual clothing gather for a teambuilding activity in a picnic shelter

Who We Are

Faculty and Staff

Meet our dedicated faculty and staff, whose expertise and commitment drive our mission and foster a dynamic learning environment.

Graduate Students

Meet our current students, who are actively contributing to cutting-edge research and advancing their fields within the department.

Alumni

Explore the achievements of our alumni, who exemplify the success and impact of our department's education and training.

Medicinal Chemistry News

the biotech one building at v.c.u.

Feb. 15, 2026

Department of Medicinal Chemistry names 2024-25 awardees

The department named five students and postdoctoral fellows as winners of six awards.

Umesh Desai, Ph.D. (left), chair of medicinal chemistry in the VCU School of Pharmacy, and Bhaumik Patel, M.D., of the Central Virginia VA Health Care System, are developing novel therapies that target cancer stem cells to help prevent tumor recurrence. (Photo by Karl E. Steinbrenner

Jan. 16, 2026

No short cuts – but a bit of sugar – in the quest to fight cancer relapse

VCU medicinal chemist Umesh Desai has spent decades exploring a frontier of biology, and the molecule he helped develop shows notable promise.

Six people, including a student in formal business attire who has just completed her dissertation defense, smile together for a photo in front of a chalkboard with computational medicinal chemistry formulas written on it.

Dec. 11, 2025

Dr. Fayyad successfully defends dissertation

Rawan Fayyad, Ph.D., defended her dissertation this month and has earned her Ph.D. in pharmaceutical sciences with a concentration in medicinal chemistry.