Department of Medicinal Chemistry

Discovering and developing new therapeutic agents and targets

Medicinal chemistry, a multidisciplinary field integrating chemistry and the life sciences, applies chemical principles to study biologically active substances such as therapeutically useful drugs, natural products, toxins and drugs of abuse. Our department offers advanced training in drug design and discovery, emphasizing areas such as cardiovascular drugs, central nervous system agents, antimicrobial targets, natural product biosynthesis, anti-cancer agents and biomolecule structure elucidation. With state-of-the-art molecular modeling facilities, synthetic organic chemistry laboratories, X-ray crystallographic equipment and high-field nuclear magnetic resonance spectrometers, our research is supported by cutting-edge technologies and collaborations with the Center for Drug Discovery.

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Degree Offerings

Our M.S. and Ph.D. programs offer an in-depth study of synthesizing, analyzing and designing pharmaceutical compounds.

Two current students celebrate the graduation of their Medicinal Chemistry peer at the Hooding and Diploma Ceremony while another graduate and their professor and mentor take photos of them posing together with flowers

Research

Our department is a leader in drug discovery and development.

Postdoctoral fellow Ennian Li presents research to industry partners at the school's Research Day

Courses

Review a list of medicinal chemistry courses on the VCU Bulletin site.

Students in the audience of a lecture hall share a laugh prior to the beginnning of a session at the Medicinal Chemistry Symposium

Graduate Student Association

Explore the alpha chapter of the nationally-recognized ACS MEDI Division.

Students and faculty in casual clothing gather for a teambuilding activity in a picnic shelter

Who We Are

Faculty and Staff

Meet our dedicated faculty and staff, whose expertise and commitment drive our mission and foster a dynamic learning environment.

Graduate Students

Meet our current students, who are actively contributing to cutting-edge research and advancing their fields within the department.

Alumni

Explore the achievements of our alumni, who exemplify the success and impact of our department's education and training.

Medicinal Chemistry News

the biotech one building at v.c.u.

Sept. 12, 2025

Ph.D. candidate wins poster presentation award at Walter Lawrence Cancer Retreat

Ally Thompson won one of three poster presentation awards at the recent event, hosted by VCU Massey Comprehensive Cancer Center.

Portraits of Dr. Yana Cen and Dr. Hylton Gravatt on a gold background

Sept. 11, 2025

Drs. Cen and Hylton Gravatt named VCU faculty awardees for research and teaching excellence

These awardees, who raise the number of such honorees at VCU SoP to five in the last three years, will be recognized at the university's Faculty Recognition Gala in October.

Piyusha Pagare

Sept. 5, 2025

VCU researcher’s opioid use disorder project earns NIH Director’s Pioneer Award

Medicinal chemist Piyusha Pagare’s new project will focus on counteracting the lethal effect of synthetic opioids like fentanyl.